Alternation of Glomerular Eicosanoid Metabolism in Spontaneous Hypertensive Rats
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چکیده
منابع مشابه
Water Metabolism in Hypertensive Rats
The water intake in hypertensive rats was investigated. Rats made hypertensive by renal ischemia increased their water consumption by 75 per cent over the preoperative level. Polyuria was associated with this polydipsia and the independence of these occurrences from a number of other factors was demonstrated. It was found that the presence of a normal kidney exerted a compensatory influence whi...
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The possible role of catecholamines in two forms of experimental hypertension in rats was investigated further. Inbred, spontaneously hypertensive (SH) Wistar rats had unchanged endogenous levels of norepinephrine (NE) in the three tissues studied, and a significantly (P<0.05) decreased rate of NE synthesis (C-tyrosine technique) in heart and brainstem but not in gut, in comparison to normotens...
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This study was designed to investigate the effects of dietary modification of prostaglandin (PG) synthesis on blood pressure regulation in spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats under conditions of normal and elevated salt intake. Forty rats from both strains were placed on either a two-series PG inhibitory diet of Max eicosapentaenoic acid (EPA) fish oil or a control diet...
متن کاملCholesterol metabolism in spontaneously hypertensive rats.
The absorption of radioactive cholesterol tended to be increased, and the catabolism of cholesterol detected by the decay of radioactive cholesterol in the serum after the intraperitoneal injection was delayed in ALR in comparison with normotensive WK rats. The reactive hypercholesterolemia in the ALR which had been selectively bred for a greater hypercholesterolemia was ascribed to the decreas...
متن کاملGlomerular and tubular damage in normotensive and hypertensive rats.
Tubular cell damage is an important mediator of interstitial fibrosis in chronic renal diseases. Glomerular and tubular damage in genetic hypertension was therefore studied. Tubular and glomerular damage was investigated in 10-, 40-, and 70-wk-old spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) and compared with glomerular capillary pressure (P(GC)) and glomerulosclerosis in s...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1990
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.31.566